HS-LS3.B: Variation of Traits
-
Punnett Square Worksheet – Pea Plant Genetics Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
Students will learn about the genotypes, phenotypes, and probabilities by completing this Punnett square worksheet for the different characteristics of pea plants.NGSS Standard
HS-LS3-3
Published by NGSS Life Science
-
Dragon Genetics - Online Game Free Lesson Plan
Project
Students learn heredity, meiosis, proteins, and more by playing a free online game that models the genetics of virtual dragons. Highly visual and interactive, students love playing this game! You can run the game for 5 days up to two weeks.NGSS Standard
HS-LS1-1
HS-LS3-3
Published by The Concord Consortium, Inc
-
Meiosis Quiz Question Bank Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Test
The meiosis quiz question bank includes meiosis, crossing over of homologous chromosomes, fertilization, genetic variation, and diploid and haploid chromosome numbers. You can use the question bank to build assessments, and active membership is required to view questions.NGSS Standard
HS-LS3-2
MS-LS3-2 (Types of Reproduction)
Published by NGSS Life Science
-
Genetics Test Question Bank Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Test
Genetics question bank to help you build assessments. An active membership is required to view questions.NGSS Standard
HS-LS3-3
Published by NGSS Life Science
-
BLAST Cancer RAS Gene Project Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Project
Students will do a BLAST and learn about how a mutated gene will code for an abnormal protein, affecting the organism’s phenotype.NGSS Standard
HS-LS1-1
HS-LS1-4
HS-LS3-1
HS-LS3-2
HS-LS4-1
Published by NGSS Life Science
-
Meiosis Worksheet - Linked Genes Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
In this advanced meiosis worksheet, students will practice citing evidence of gene linkage using crossover frequencies to defend a claim.NGSS Standard
HS-LS3-1
HS-LS3-2
Published by NGSS Life Science
-
Genetic Variation Test Question Bank Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Test
Question bank to build assessments. An active membership is required to view questions.NGSS Standard
HS-LS1-1
HS-LS3-2
Published by NGSS Life Science
-
Genetics with SpongeBob - Dihybrid Crosses Free Lesson Plan
Worksheet
Students complete dihybird crosses about SpongeBob. SpongeBob SquarePants and all related characters are trademarks of Viacom International Inc.NGSS Standard
HS-LS3-3
Published by Andrea Stonebraker
-
Blood Type Genetics Lab Free Student Handout
Free Teacher Notes
Lab
In this blood typing lab, students pretend to investigate blood samples (actually simple chemicals) and use their analysis of the experiment to solve a crime and determine if two babies were switched in the hospital.NGSS Standard
HS-LS3-3
Published by Ingrid Waldron and Jennifer Doherty
-
Independent Assortment and Gene Linkage Lab - Dragon Genetics Free Student Handout
Free Teacher Notes
Lab
Students learn the principles of independent assortment and gene linkage in activities that analyze the inheritance of multiple genes on the same or different chromosomes in hypothetical dragons. The concepts of independent assortment of chromosomes during meiosis and random fertilization are modeled with linked genes.NGSS Standard
HS-LS1-4
HS-LS3-3
Published by Ingrid Waldron and Jennifer Doherty
-
Demystifying Punnett Squares Simulation Free Multimedia
Lab
In the simulation, students breed pairs of mice with different fur colors and observe the phenotypic ratios in the resulting offspring. Students select one breeding pair from the nest to investigate the ratios of fur color phenotypes, genotypes, and sex. Students then click “breed”. After each parent pair breeding, the resulting litter of offspring is shown, along with a pie chart, which updates to display the ratios in the total number of offspring for those parent mice.
Example questions to ask students:
Why do some of the pie charts change as you breed the mice?
Why do the pie charts stabilize?
Where are the numbers different from the ratios in Punnett Square? Where are they the same?NGSS Standard
HS-LS3-3
Published by Concord Consortium
-
Punnett Square Worksheet - Fruit Fly Genetics Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
In this Punnet square worksheet, students will learn about the genotypes, phenotypes, and probabilities of genetics for different characteristics of fruit flies.NGSS Standard
HS-LS3-3
Published by NGSS Life Science
-
Meiosis & Genetic Variation Worksheet Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
Students answer questions meiosis, asexual / sexual reproduction, fertilization, karyotypes, and genetic variation.NGSS Standard
HS-LS3-2
Published by NGSS Life Science
-
Mitosis vs. Meiosis Worksheet Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
Students answer introductory questions about the similarities and differences between mitosis and meiosis.NGSS Standard
HS-LS1-4
HS-LS3-2
Published by NGSS Life Science
-
Autosomal Pedigrees Worksheet Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
Students will learn how to use pedigrees to trace a autosomal genes as they pass from generation to the next generation. Students will also learn about genetic disorders.NGSS Standard
HS-LS3-3
Published by NGSS Life Science
-
Genetics with SpongeBob - Incomplete Dominance Free Lesson Plan
Worksheet
This worksheet provides several practice problems related to incomplete dominance with Poofkins (a special kind of flower) and Goobers (a special breed of jellyfish!) An answer key is provided. SpongeBob SquarePants and all related characters are trademarks of Viacom International Inc.NGSS Standard
HS-LS3-3
Published by Tracy Trimpe
-
SpongeBob Genetics Quiz Free Lesson Plan
Test
This SpongeBob genetics quiz includes heterozygous, homozygous, dominant, recessive, phenotype, genotype, and Punnett squares. SpongeBob SquarePants and all related characters are trademarks of Viacom International Inc.NGSS Standard
HS-LS3-3
Published by Tracy Trimpe
-
Punnett Square Genetics with SpongeBob #2 Free Lesson Plan
Worksheet
A second helping of Bikini Bottom fun exploring the genetics of SpongeBob and his pals! An answer key is provided. SpongeBob SquarePants and all related characters are trademarks of Viacom International Inc.NGSS Standard
HS-LS3-3
Published by Tracy Trimpe
-
Punnett Square Genetics with SpongeBob #1 Free Lesson Plan
Worksheet
What happens when SpongeBob SquarePants marries SpongeSusie RoundPants? Explore the genetics of Sponge Bob and his pals with this fun worksheet! An answer key is provided! SpongeBob SquarePants and all related characters are trademarks of Viacom International Inc.NGSS Standard
HS-LS3-3
Published by Tracy Trimpe
-
Transcription and Translation Lab - From Gene to Protein Free Student Handout
Free Teacher Notes
Lab
In this transcription and translation lab, students learn how a gene provides the instructions for making a protein, and how a mutation in the gene for sickle cell hemoglobin can result in sickle cell anemia. Students use paper models to transcribe and translate the DNA into a protein.NGSS Standard
HS-LS1-1
HS-LS3-1
HS-LS3-2
MS-LS3-1 (Mutations)
Published by Ingrid Waldron and Jennifer Doherty
-
Genetics Lab - Introduction Free Student Handout
Free Teacher Notes
Lab
In this genetics lab, students are introduced to genetics vocabulary, including meiosis, fertilization, Punnett squares, and pedigree analysis. Students flip coins to mimic the probability of genetics and use the coin flip results to answer inheritance questions.NGSS Standard
HS-LS3-3
Published by Ingrid Waldron and Jennifer Doherty
-
Chromosome Modeling Lab - Mitosis, Meiosis and Fertilization Free Student Handout
Free Teacher Notes
Lab
In this chromosome modeling lab, students create pairs of socks models of chromosomes to model the processes of mitosis, meiosis, and fertilization. Students also build a foundation about meiosis and fertilization and how it relates to genetics and genetic disorders.NGSS Standard
HS-LS1-4
HS-LS3-1
HS-LS3-2
Published by Ingrid Waldron and Jennifer Doherty
-
Dihybrid Cross Worksheet Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
In this dihybrid cross worksheet, students will practice performing two trait crosses. Students will cross different parental genotypes and determine the offspring phenotype, and probabilities of having each trait. The last question asks students to make the connection between multiple traits and Mendel’s law of independent assortment.NGSS Standard
HS-LS3-3
Published by NGSS Life Science
-
Punnett Square Worksheet - Human Genetic Disorders Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
In this Punnett square worksheet, students will learn about human genetic disorders for autosomal, sex-linked, pleiotropy, and incomplete dominant traits. Students will cross different parental genotypes and determine the offspring genotype, phenotype, and probabilities of having the genetic disorder and being a carrier of the genetic disorder.NGSS Standard
HS-LS3-3
Published by NGSS Life Science
-
Punnett Square Worksheet - Incomplete Dominant and Codominant Traits Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
Students will learn the difference between incomplete dominance and codominant traits by completing Punnett squares.NGSS Standard
HS-LS3-3
Published by NGSS Life Science
-
Heredity Lab Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Lab
Students will model how DNA is passed from parent to offspring to cause the physical traits of a fictitious baby.NGSS Standard
HS-LS3-3
Published by NGSS Life Science
-
Mendelian Dragon Genetics Lab Free Student Handout
Free Teacher Notes
Lab
In this genetics lab, students use Popsicle sticks to represent a pair of homologous chromosomes with multiple genetic traits. Teams of students use their sets of Popsicle sticks to model fertilization and then identify the genetic makeup and phenotypic traits, resulting in a fictitious baby dragon.NGSS Standard
HS-LS3-3
MS-LS3-2 (Types of Reproduction)
Published by Ingrid Waldron and Jennifer Doherty
-
Diploid vs Haploid Worksheet Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
In this meiosis chromosome worksheet, students answer questions about the number of chromosomes generated by either mitosis or meiosis. Haploid and diploid chromosome numbers help students understand the reproduction type used in each process.NGSS Standard
HS-LS1-4
HS-LS3-1
HS-LS3-2
MS-LS3-2 (Types of Reproduction)
Published by NGSS Life Science
-
Understanding Cancer Free Multimedia
Free Teacher Notes
Multimedia
This is a great information webpage about what is cancer, the kinds of cancer, screening methods, causes, oncogenes, tumor suppressor genes, and so much more. The teacher notes is about myths and misconceptions around commonly asked questions about cancer.NGSS Standard
HS-LS1-4
HS-LS3-2
HS-LS3-3
Published by National Cancer Institute