HS-LS1.A: Structure and Function
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Protein Synthesis Worksheet Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
In this protein synthesis worksheet, students will practice the process of transcription and translation. Students will transcribe DNA into RNA using the base pairing rules. Then students will translate that RNA to build a polypeptide. Students will also answer review questions about transcription and translation. This protein synthesis worksheet is a great skill builder for understanding the vocabulary in both processes and DNA base pairing rules.NGSS Standard
HS-LS1-1
Published by NGSS Life Science
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Enzyme Worksheet Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Worksheet
Students will be introduced to enzyme substrate system, activation energy, and that temperature affects enzyme activity.NGSS Standard
HS-LS1-3
Published by NGSS Life Science
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Dragon Genetics - Online Game Free Lesson Plan
Project
Students learn heredity, meiosis, proteins, and more by playing a free online game that models the genetics of virtual dragons. Highly visual and interactive, students love playing this game! You can run the game for 5 days up to two weeks.NGSS Standard
HS-LS1-1
HS-LS3-3
Published by The Concord Consortium, Inc
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BLAST Cancer RAS Gene Project Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Project
Students will do a BLAST and learn about how a mutated gene will code for an abnormal protein, affecting the organism’s phenotype.NGSS Standard
HS-LS1-1
HS-LS1-4
HS-LS3-1
HS-LS3-2
HS-LS4-1
Published by NGSS Life Science
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Human Body Systems Disorder Project Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Project
Students will do a BLAST and learn about how the mutated protein affects cells, organs, and organ systems and those systems overall impact on homeostasis. The example students will use is sickle cell disorder.NGSS Standard
HS-LS1-1
HS-LS1-2
HS-LS1-3
Published by NGSS Life Science
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Design a Homeostasis Lab Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Lab
This is an introductory lesson into how to design an experiment. Students will practice writing a hypothesis. Students will create procedures to conduct their own experiment. Students will create a data table for their experimental data. Students will write a conclusion that has them focus on evidence from their experiment.NGSS Standard
HS-LS1-3
Published by NGSS Life Science
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Protein Synthesis Test Question Bank Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Test
Question bank to build assessments. An active membership is required to view questions.NGSS Standard
HS-LS1-1
Published by NGSS Life Science
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Homeostasis Test Question Bank Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Test
Question bank to build assessments. An active membership is required to view questions.NGSS Standard
HS-LS1-3
Published by NGSS Life Science
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Genetic Variation Test Question Bank Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Test
Question bank to build assessments. An active membership is required to view questions.NGSS Standard
HS-LS1-1
HS-LS3-2
Published by NGSS Life Science
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Body Systems Interactions Test Question Bank Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Free Lesson Plan
Test
Question bank to build assessments. An active membership is required to view questions.NGSS Standard
HS-LS1-2
Published by NGSS Life Science
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How HIV Infects Cells - AP Free Lesson Plan
Worksheet
Students read about how HIV infects cells, answer 3 questions, and then color the virus / cell parts for 15 keywords.NGSS Standard
HS-LS1-2
MS-LS1-3 (HBS)
Published by Shannan Muskopf
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External Anatomy of a Frog Free Lesson Plan
Lab
The eyes, legs, and mouth of the frog is dissected and analyzed.NGSS Standard
HS-LS1-2
MS-LS1-3 (HBS)
MS-LS1-4 (Animal Plant Structures)
Published by Shannan Muskopf
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Fetal Pig Dissection Free Lesson Plan
Lab
Fetal Pig dissection lab manual.NGSS Standard
HS-LS1-2
MS-LS1-3 (HBS)
MS-LS1-4 (Animal Plant Structures)
Published by Shannan Muskopf
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Enzyme Lab Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Lab
In this enzyme lab, students will discover the effects temperature, pH, and substrate concentration has on enzyme activity. Students will experiment on the enzyme catalase in different foods to determine its qualitative rate of reaction. This enzyme lab asks students to transfer the enzyme activity concepts in this experiment to homeostasis in organisms.NGSS Standard
HS-LS1-3
Published by NGSS Life Science
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Plant Growth Homeostasis Lab Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Lab
Students will learn how to disrupt homeostasis in plants and use this disruption to understand biological processes. Students will be able to integrate how many processes are involved for plants to grow. Students will be able to design a guided inquiry experiment.NGSS Standard
HS-LS1-3
HS-LS1-4
HS-LS1-5
HS-LS1-6
HS-LS1-7
Common Core Standard
RST 9.10.3, 9.10.5, 9.10.7, WST 9.10.1b, 9.10.1e, 9.10.2a, 9.10.7, 9.10.9
Published by NGSS Life Science
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Enzymes Test Question Bank Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Test
Question bank to build assessments. An active membership is required to view questions.NGSS Standard
HS-LS1-3
Published by NGSS Life Science
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Characteristics of Life Lab Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Lab
Students will learn use their observation skills to determine if an object is living, dead, dormant, a product of a living thing, or never alive using the main characteristics of life.NGSS Standard
HS-LS1-3
HS-LS4-2
MS-LS1-1 (Cell Types)
Published by NGSS Life Science
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Human Body Wanted Poster Project Free Lesson Plan
Project
Students will create a to create a "Wanted" poster about an organ. Students will research an organ system contains your organ, the organ's main functions, ow does your organ works with other systems to keep the body healthy, which diseases or disorders affects your organ, and can a person live without the organ.NGSS Standard
HS-LS1-2
MS-LS1-3 (HBS)
MS-LS1-8 (Brain)
Published by Stacy Baker & Tracy Trimpe
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How DNA Controls the Workings of the Cell Free Lesson Plan
Worksheet
Students are given two partial sequences of DNA bases for the gene insulin, 1 is from a human and 2 is from a cow. Students transcribe and translate the code and then analyze the sequence for mutations.NGSS Standard
HS-LS1-1
MS-LS3-1 (Mutations)
Published by Shannan Muskopf
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Circulatory System Lab - Heart Rate Regulation Free Student Handout
Free Teacher Notes
Lab
In this heart rate lab, students learn how to measure heart rate and then they design an experiment to test the effects of an activity or stimulus on heart rate. In their lab report, students analyze and interpret the experimental data, and culminate with a presentation of their experiment to the class.NGSS Standard
HS-LS1-2
HS-LS1-3
MS-LS1-3 (HBS)
Published by Ingrid Waldron and Jennifer Doherty
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Transcription and Translation Lab - From Gene to Protein Free Student Handout
Free Teacher Notes
Lab
In this transcription and translation lab, students learn how a gene provides the instructions for making a protein, and how a mutation in the gene for sickle cell hemoglobin can result in sickle cell anemia. Students use paper models to transcribe and translate the DNA into a protein.NGSS Standard
HS-LS1-1
HS-LS3-1
HS-LS3-2
MS-LS3-1 (Mutations)
Published by Ingrid Waldron and Jennifer Doherty
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DNA Extraction Lab Free Student Handout
Free Teacher Notes
Lab
In this DNA lab, students extract DNA from their cheek cells to learn about the structure of DNA and DNA replication. The lab has students think about why they were using each reagent and how that relates to the polarity of lipids. Students answer questions regarding DNA base pairing and it relates to the central dogma (DNA - Proteins - Traits).NGSS Standard
HS-LS1-1
HS-LS3-1
Published by Ingrid Waldron and Jennifer Doherty
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Sense of Taste Lab Free Student Handout
Free Teacher Notes
Lab
In this lab about the sense of smell and taste, students investigate how a person identifies different flavors of jellybeans. Students learn about the olfactory receptors and the olfactory bulb transmit information to the brain and how the brain interprets salt, sweet, sour, bitter, or savory flavors.NGSS Standard
HS-LS1-2
MS-LS1-3 (HBS)
MS-LS1-8 (Brain)
Published by Ingrid Waldron and Jennifer Doherty
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DNA to Me Lyrics Project Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Project
In this protein synthesis project, students will write a poem or music lyrics about DNA, protein synthesis, and phenotypes. This DNA project is a culmination of what students who have already learned about DNA structure, DNA base pairing, genes, transcription, translation, and phenotypes.NGSS Standard
HS-LS1-1
HS-LS1-6
HS-LS3-1
Published by NGSS Life Science
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Gene Expression - Ghost in Your Genes Free Lesson Plan
Free Video
Lab
Students model how scientists use DNA microarrays to determine levels of gene expression in breast cancer patients, and then choose treatments based on what they learn.NGSS Standard
HS-LS1-1
HS-LS3-1
Published by Margy Kuntz and NOVA / PBS
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Human Body Systems Word Search Free Lesson Plan
Worksheet
A word search with 31 terms related to the human body systems.NGSS Standard
HS-LS1-2
MS-LS1-3 (HBS)
MS-LS1-8 (Brain)
Published by Tracy Trimpe
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Nervous System Crossword Free Lesson Plan
Worksheet
17 question crossword puzzle about the nervous system.NGSS Standard
HS-LS1-2
MS-LS1-8 (Brain)
Published by Tracy Trimpe
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Skeletal & Muscular System Crossword Free Lesson Plan
Worksheet
19 question crossword puzzle about the skeletal and muscular systems.NGSS Standard
HS-LS1-2
MS-LS1-3 (HBS)
Published by Tracy Trimpe
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Aerobic and Anaerobic Respiration Lab: Breathing and Holding Your Breath Free Student Handout
Free Teacher Notes
Lab
In this aerobic and anaerobic respiration lab, students learn a basic understanding of the regulation of breathing. Students then design an experiment to test whether changing oxygen and carbon dioxide levels in their bodies influence how long they can hold their breath.NGSS Standard
HS-LS1-2
HS-LS1-3
Published by Ingrid Waldron and Jennifer Doherty
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Biological Acids and Bases Lab Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Lab
In this introductory acids and bases lab, students will determine the pH of common household acids and bases and transfer their knowledge about acids and bases to the human body's homeostasis. This lab is an easy hands-on biochemistry lesson to introduce homeostasis to students.NGSS Standard
HS-LS1-3
Published by NGSS Life Science
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3D Simulation of Antibody and Antigen Free Multimedia
Multimedia
Students will observe a 3D model of antibodies and antigens. Students can rotate the model. The goal is for students to chemically observe how shape determines function.NGSS Standard
HS-LS1-1
Published by Concord Consortium
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Enzyme Specificity Lab Free Student Handout
Free Teacher Notes
Lab
Students learn how enzymes function how they bind to specific substrates using lactose and sucrose. 3 mini experiments are included in this lesson plan.NGSS Standard
HS-LS1-3
Published by Ingrid Waldron and Jennifer Doherty
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Kindney - Nephron - Bowmen’s Capsule - AP Free Lesson Plan
Worksheet
Students color in the different parts of a kidney, nephron, and Bowmans capsule and then answer 5 analysis questions.NGSS Standard
HS-LS1-2
MS-LS1-3 (HBS)
Published by Shannan Muskopf
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Human Population Growth Lab - Spread of an Infectious Disease Free Student Handout
Free Teacher Notes
Lab
In this human population growth lab, students simulate the exponential growth of an infectious disease in a population. Students then discuss how human diseases spread and their exponential and logistic growth curves. Lastly, students graph the simulated results.NGSS Standard
HS-LS1-2
Published by Ingrid Waldron and Jennifer Doherty
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Food Chain Lab - Owl Pellets Free Student Handout
Lab
In this food chain lab, students dissect owl pellets to learn how the owl is part of a food chain. Since the owl regurgitates these compact pellets, owl pellets are undigested parts that the owl eats, which contain fur and bones of small rodents. Dry pellets will not smell and are acceptable for students to handle with gloves.NGSS Standard
HS-LS1-2
HS-LS2-4
MS-LS1-7 (Metabolism)
MS-LS2-1 (Resource Availability)
Published by Shannan Muskopf