Biotechnology
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BLAST Cancer RAS Gene Project Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Project
Students will do a BLAST and learn about how a mutated gene will code for an abnormal protein, affecting the organism’s phenotype.NGSS Standard
HS-LS1-1
HS-LS1-4
HS-LS3-1
HS-LS3-2
HS-LS4-1
Published by NGSS Life Science
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Human Body Systems Disorder Project Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Project
Students will do a BLAST and learn about how the mutated protein affects cells, organs, and organ systems and those systems overall impact on homeostasis. The example students will use is sickle cell disorder.NGSS Standard
HS-LS1-1
HS-LS1-2
HS-LS1-3
Published by NGSS Life Science
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Blood Type Genetics Lab Free Student Handout
Free Teacher Notes
Lab
In this blood typing lab, students pretend to investigate blood samples (actually simple chemicals) and use their analysis of the experiment to solve a crime and determine if two babies were switched in the hospital.NGSS Standard
HS-LS3-3
Published by Ingrid Waldron and Jennifer Doherty
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Recombinant Paper Plasmids Free Lesson Plan
Free Video
Lab
Biomedical engineers use recombinant DNA technologies with the goal of curing genetic diseases & cancer, and to improve agricultural yields. Students will model several of the steps of restriction enzymes to build plamids.NGSS Standard
HS-LS3-1
Published by Ely Science Center
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Strawberry DNA Extraction Lab Free Lesson Plan (PDF)
Lesson Plan (DOCX) & Answer Key with Membership
Lab
Students will extract DNA from both bananas and strawberries. This is a great lab to do while introducing biomolecules for nucleic acids.NGSS Standard
HS-LS3-1
Published by NGSS Life Science
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Cracking the Code of Life Free Video
Multimedia
This NOVA video covers topics including the human genome, mutations, genetic variations, the supreme court decision to patent genes, finding cures to diseases, and genetic modification.NGSS Standard
HS-LS3-1
Published by WGBH Educational Foundation and Clear Blue Sky Productions
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Genetic Ethics Questions Free Lesson Plan
Worksheet
Students answer multiple choice questions on science ethics relating to genetics (cloning, gene therapy). The class then discusses the pros and cons of each of the questions.NGSS Standard
HS-LS3-1
Published by Shannan Muskopf
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DNA Extraction Lab Free Student Handout
Free Teacher Notes
Lab
In this DNA lab, students extract DNA from their cheek cells to learn about the structure of DNA and DNA replication. The lab has students think about why they were using each reagent and how that relates to the polarity of lipids. Students answer questions regarding DNA base pairing and it relates to the central dogma (DNA - Proteins - Traits).NGSS Standard
HS-LS1-1
HS-LS3-1
Published by Ingrid Waldron and Jennifer Doherty
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Bacteria Transformation Free Lesson Plan
Lab
Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role restriction enzymes, DNA ligase, and genes play in the modification of organisms. This activity will use the insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for the production of the protein insulin for medicine.NGSS Standard
HS-LS3-1
Published by Teach Engineering
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Gene Expression - Ghost in Your Genes Free Lesson Plan
Free Video
Lab
Students model how scientists use DNA microarrays to determine levels of gene expression in breast cancer patients, and then choose treatments based on what they learn.NGSS Standard
HS-LS1-1
HS-LS3-1
Published by Margy Kuntz and NOVA / PBS
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DNA Fingerprinting Crime Scene Free Lesson Plan
Worksheet
Students will examine crime scene evidence to determine who is responsible for eating the Queen's special imported Lindbergher Cheese. Students will model the process of electrophoresis and DNA fingerprinting.NGSS Standard
HS-LS3-1
Published by Shannan Muskopf